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Epigenomic enhancer annotation reveals a key role for NFIX in neural stem cell quiescence

The majority of neural stem cells (NSCs) in the adult brain are quiescent, and this fraction increases with aging. Although signaling pathways that promote NSC quiescence have been identified, the transcriptional mechanisms involved are mostly unknown, largely due to lack of a cell culture model. In...

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Detalles Bibliográficos
Autores principales: Martynoga, Ben, Mateo, Juan L., Zhou, Bo, Andersen, Jimena, Achimastou, Angeliki, Urbán, Noelia, van den Berg, Debbie, Georgopoulou, Dimitra, Hadjur, Suzana, Wittbrodt, Joachim, Ettwiller, Laurence, Piper, Michael, Gronostajski, Richard M., Guillemot, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759694/
https://www.ncbi.nlm.nih.gov/pubmed/23964093
http://dx.doi.org/10.1101/gad.216804.113