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The Soluble Form of the Cellular Prion Protein Enhances Phagocytic Activity and Cytokine Production by Human Monocytes Via Activation of ERK and NF-κB
The PrP(C) is expressed in many types of immune cells including monocytes and macrophages, however, its function in immune regulation remains to be elucidated. In the present study, we examined a role for PrP(C) in regulation of monocyte function. Specifically, the effect of a soluble form of PrP(C)...
Autores principales: | Jeon, Jae-Won, Park, Bum-Chan, Jung, Joon-Goo, Jang, Young-Soon, Shin, Eui-Cheol, Park, Young Woo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Immunologists
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759712/ https://www.ncbi.nlm.nih.gov/pubmed/24009542 http://dx.doi.org/10.4110/in.2013.13.4.148 |
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