Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most deadly cancers worldwide and has no effective treatment, yet the molecular basis of hepatocarcinogenesis remains largely unknown. Here we report findings from a whole-genome sequencing (WGS) study of 88 matched HCC tumor/normal pairs, 81 of which are...

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Detalles Bibliográficos
Autores principales: Kan, Zhengyan, Zheng, Hancheng, Liu, Xiao, Li, Shuyu, Barber, Thomas D., Gong, Zhuolin, Gao, Huan, Hao, Ke, Willard, Melinda D., Xu, Jiangchun, Hauptschein, Robert, Rejto, Paul A., Fernandez, Julio, Wang, Guan, Zhang, Qinghui, Wang, Bo, Chen, Ronghua, Wang, Jian, Lee, Nikki P., Zhou, Wei, Lin, Zhao, Peng, Zhiyu, Yi, Kang, Chen, Shengpei, Li, Lin, Fan, Xiaomei, Yang, Jie, Ye, Rui, Ju, Jia, Wang, Kai, Estrella, Heather, Deng, Shibing, Wei, Ping, Qiu, Ming, Wulur, Isabella H., Liu, Jiangang, Ehsani, Mariam E., Zhang, Chunsheng, Loboda, Andrey, Sung, Wing Kin, Aggarwal, Amit, Poon, Ronnie T., Fan, Sheung Tat, Wang, Jun, Hardwick, James, Reinhard, Christoph, Dai, Hongyue, Li, Yingrui, Luk, John M., Mao, Mao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759719/
https://www.ncbi.nlm.nih.gov/pubmed/23788652
http://dx.doi.org/10.1101/gr.154492.113

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