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Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods

Recent advancements in sequencing-based DNA methylation profiling methods provide an unprecedented opportunity to map complete DNA methylomes. These include whole-genome bisulfite sequencing (WGBS, MethylC-seq, or BS-seq), reduced-representation bisulfite sequencing (RRBS), and enrichment-based meth...

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Detalles Bibliográficos
Autores principales: Stevens, Michael, Cheng, Jeffrey B., Li, Daofeng, Xie, Mingchao, Hong, Chibo, Maire, Cécile L., Ligon, Keith L., Hirst, Martin, Marra, Marco A., Costello, Joseph F., Wang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759729/
https://www.ncbi.nlm.nih.gov/pubmed/23804401
http://dx.doi.org/10.1101/gr.152231.112