Tau Clearance Mechanisms and Their Possible Role in the Pathogenesis of Alzheimer Disease

One of the defining pathological features of Alzheimer disease (AD) is the intraneuronal accumulation of tau. The tau that forms these accumulations is altered both posttranslationally and conformationally, and there is now significant evidence that soluble forms of these modified tau species are th...

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Detalles Bibliográficos
Autores principales: Chesser, Adrianne S., Pritchard, Susanne M., Johnson, Gail V. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759803/
https://www.ncbi.nlm.nih.gov/pubmed/24027553
http://dx.doi.org/10.3389/fneur.2013.00122

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