Functional Diversity of RNAi-Associated sRNAs in Fungi

Yeast and filamentous fungi have been essential model systems for unveiling the secrets of RNA interference (RNAi). Research on these organisms has contributed to identifying general mechanisms and conserved eukaryotic RNAi machinery that can be found from fungi to mammals. The development of deep s...

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Detalles Bibliográficos
Autores principales: Nicolás, Francisco E., Ruiz-Vázquez, Rosa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759863/
https://www.ncbi.nlm.nih.gov/pubmed/23887655
http://dx.doi.org/10.3390/ijms140815348
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author Nicolás, Francisco E.
Ruiz-Vázquez, Rosa M.
author_facet Nicolás, Francisco E.
Ruiz-Vázquez, Rosa M.
author_sort Nicolás, Francisco E.
collection PubMed
description Yeast and filamentous fungi have been essential model systems for unveiling the secrets of RNA interference (RNAi). Research on these organisms has contributed to identifying general mechanisms and conserved eukaryotic RNAi machinery that can be found from fungi to mammals. The development of deep sequencing technologies has brought on the last wave of studies on RNAi in fungi, which has been focused on the identification of new types of functional small RNAs (sRNAs). These studies have discovered an unexpected diversity of sRNA, biogenesis pathways and new functions that are the focus of this review.
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spelling pubmed-37598632013-09-03 Functional Diversity of RNAi-Associated sRNAs in Fungi Nicolás, Francisco E. Ruiz-Vázquez, Rosa M. Int J Mol Sci Review Yeast and filamentous fungi have been essential model systems for unveiling the secrets of RNA interference (RNAi). Research on these organisms has contributed to identifying general mechanisms and conserved eukaryotic RNAi machinery that can be found from fungi to mammals. The development of deep sequencing technologies has brought on the last wave of studies on RNAi in fungi, which has been focused on the identification of new types of functional small RNAs (sRNAs). These studies have discovered an unexpected diversity of sRNA, biogenesis pathways and new functions that are the focus of this review. Molecular Diversity Preservation International (MDPI) 2013-07-24 /pmc/articles/PMC3759863/ /pubmed/23887655 http://dx.doi.org/10.3390/ijms140815348 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland http://creativecommons.org/licenses/by/3.0 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Nicolás, Francisco E.
Ruiz-Vázquez, Rosa M.
Functional Diversity of RNAi-Associated sRNAs in Fungi
title Functional Diversity of RNAi-Associated sRNAs in Fungi
title_full Functional Diversity of RNAi-Associated sRNAs in Fungi
title_fullStr Functional Diversity of RNAi-Associated sRNAs in Fungi
title_full_unstemmed Functional Diversity of RNAi-Associated sRNAs in Fungi
title_short Functional Diversity of RNAi-Associated sRNAs in Fungi
title_sort functional diversity of rnai-associated srnas in fungi
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759863/
https://www.ncbi.nlm.nih.gov/pubmed/23887655
http://dx.doi.org/10.3390/ijms140815348
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