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Early Lung Cancer Diagnosis by Biosensors
Lung cancer causes an extreme threat to human health, and the mortality rate due to lung cancer has not decreased during the last decade. Prognosis or early diagnosis could help reduce the mortality rate. If microRNA and tumor-associated antigens (TAAs), as well as the corresponding autoantibodies,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759869/ https://www.ncbi.nlm.nih.gov/pubmed/23892596 http://dx.doi.org/10.3390/ijms140815479 |
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author | Zhang, Yuqian Yang, Dongliang Weng, Lixing Wang, Lianhui |
author_facet | Zhang, Yuqian Yang, Dongliang Weng, Lixing Wang, Lianhui |
author_sort | Zhang, Yuqian |
collection | PubMed |
description | Lung cancer causes an extreme threat to human health, and the mortality rate due to lung cancer has not decreased during the last decade. Prognosis or early diagnosis could help reduce the mortality rate. If microRNA and tumor-associated antigens (TAAs), as well as the corresponding autoantibodies, can be detected prior to clinical diagnosis, such high sensitivity of biosensors makes the early diagnosis and prognosis of cancer realizable. This review provides an overview of tumor-associated biomarker identifying methods and the biosensor technology available today. Laboratorial researches utilizing biosensors for early lung cancer diagnosis will be highlighted. |
format | Online Article Text |
id | pubmed-3759869 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-37598692013-09-03 Early Lung Cancer Diagnosis by Biosensors Zhang, Yuqian Yang, Dongliang Weng, Lixing Wang, Lianhui Int J Mol Sci Review Lung cancer causes an extreme threat to human health, and the mortality rate due to lung cancer has not decreased during the last decade. Prognosis or early diagnosis could help reduce the mortality rate. If microRNA and tumor-associated antigens (TAAs), as well as the corresponding autoantibodies, can be detected prior to clinical diagnosis, such high sensitivity of biosensors makes the early diagnosis and prognosis of cancer realizable. This review provides an overview of tumor-associated biomarker identifying methods and the biosensor technology available today. Laboratorial researches utilizing biosensors for early lung cancer diagnosis will be highlighted. MDPI 2013-07-25 /pmc/articles/PMC3759869/ /pubmed/23892596 http://dx.doi.org/10.3390/ijms140815479 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland http://creativecommons.org/licenses/by/3.0 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Zhang, Yuqian Yang, Dongliang Weng, Lixing Wang, Lianhui Early Lung Cancer Diagnosis by Biosensors |
title | Early Lung Cancer Diagnosis by Biosensors |
title_full | Early Lung Cancer Diagnosis by Biosensors |
title_fullStr | Early Lung Cancer Diagnosis by Biosensors |
title_full_unstemmed | Early Lung Cancer Diagnosis by Biosensors |
title_short | Early Lung Cancer Diagnosis by Biosensors |
title_sort | early lung cancer diagnosis by biosensors |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759869/ https://www.ncbi.nlm.nih.gov/pubmed/23892596 http://dx.doi.org/10.3390/ijms140815479 |
work_keys_str_mv | AT zhangyuqian earlylungcancerdiagnosisbybiosensors AT yangdongliang earlylungcancerdiagnosisbybiosensors AT wenglixing earlylungcancerdiagnosisbybiosensors AT wanglianhui earlylungcancerdiagnosisbybiosensors |