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Impaired Pre-mRNA Processing and Altered Architecture of 3′ Untranslated Regions Contribute to the Development of Human Disorders
The biological fate of each mRNA and consequently, the protein to be synthesised, is highly dependent on the nature of the 3′ untranslated region. Despite its non-coding character, the 3′ UTR may affect the final mRNA stability, the localisation, the export from the nucleus and the translation effic...
Autores principales: | Michalova, Eva, Vojtesek, Borivoj, Hrstka, Roman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759880/ https://www.ncbi.nlm.nih.gov/pubmed/23896598 http://dx.doi.org/10.3390/ijms140815681 |
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