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The Efficacy of the Quorum Sensing Inhibitor FS8 and Tigecycline in Preventing Prosthesis Biofilm in an Animal Model of Staphylococcal Infection

We investigated the efficacy of tigecycline and FS8, alone or combined, in preventing prosthesis biofilm in a rat model of staphylococcal vascular graft infection. Graft infections were established in the back subcutaneous tissue of adult male Wistar rats by implantation of Dacron prostheses followe...

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Detalles Bibliográficos
Autores principales: Simonetti, Oriana, Cirioni, Oscar, Mocchegiani, Federico, Cacciatore, Ivana, Silvestri, Carmela, Baldassarre, Leonardo, Orlando, Fiorenza, Castelli, Pamela, Provinciali, Mauro, Vivarelli, Marco, Fornasari, Erika, Giacometti, Andrea, Offidani, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759913/
https://www.ncbi.nlm.nih.gov/pubmed/23965956
http://dx.doi.org/10.3390/ijms140816321