Structural Variations in Articular Cartilage Matrix Are Associated with Early-Onset Osteoarthritis in the Spondyloepiphyseal Dysplasia Congenita (Sedc) Mouse

Heterozgyous spondyloepiphyseal dysplasia congenita (sedc/+) mice expressing a missense mutation in col2a1 exhibit a normal skeletal morphology but early-onset osteoarthritis (OA). We have recently examined knee articular cartilage obtained from homozygous (sedc/sedc) mice, which express a Stickler-...

Descripción completa

Detalles Bibliográficos
Autores principales: Macdonald, David W., Squires, Ryan S., Avery, Shaela A., Adams, Jason, Baker, Melissa, Cunningham, Christopher R., Heimann, Nicholas B., Kooyman, David L., Seegmiller, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759923/
https://www.ncbi.nlm.nih.gov/pubmed/23939426
http://dx.doi.org/10.3390/ijms140816515

Ejemplares similares

Ejemplares similares