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Mechanisms of Lin28-Mediated miRNA and mRNA Regulation—A Structural and Functional Perspective
Lin28 is an essential RNA-binding protein that is ubiquitously expressed in embryonic stem cells. Its physiological function has been linked to the regulation of differentiation, development, and oncogenesis as well as glucose metabolism. Lin28 mediates these pleiotropic functions by inhibiting let-...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Molecular Diversity Preservation International (MDPI)
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759924/ https://www.ncbi.nlm.nih.gov/pubmed/23939427 http://dx.doi.org/10.3390/ijms140816532 |