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Endogenous Protease Nexin-1 Protects against Cerebral Ischemia

The serine protease thrombin plays a role in signalling ischemic neuronal death in the brain. Paradoxically, endogenous neuroprotective mechanisms can be triggered by preconditioning with thrombin (thrombin preconditioning, TPC), leading to tolerance to cerebral ischemia. Here we studied the role of...

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Detalles Bibliográficos
Autores principales: Mirante, Osvaldo, Price, Melanie, Puentes, Wilfredo, Castillo, Ximena, Benakis, Corinne, Thevenet, Jonathan, Monard, Denis, Hirt, Lorenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759934/
https://www.ncbi.nlm.nih.gov/pubmed/23949634
http://dx.doi.org/10.3390/ijms140816719