Cargando…

Endogenous Protease Nexin-1 Protects against Cerebral Ischemia

The serine protease thrombin plays a role in signalling ischemic neuronal death in the brain. Paradoxically, endogenous neuroprotective mechanisms can be triggered by preconditioning with thrombin (thrombin preconditioning, TPC), leading to tolerance to cerebral ischemia. Here we studied the role of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mirante, Osvaldo, Price, Melanie, Puentes, Wilfredo, Castillo, Ximena, Benakis, Corinne, Thevenet, Jonathan, Monard, Denis, Hirt, Lorenz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759934/ https://www.ncbi.nlm.nih.gov/pubmed/23949634 http://dx.doi.org/10.3390/ijms140816719

Ejemplares similares

Neuroprotection by inhibiting the c-Jun N-terminal kinase pathway after cerebral ischemia occurs independently of interleukin-6 and keratinocyte-derived chemokine (KC/CXCL1) secretion
por: Benakis, Corinne, et al.
Publicado: (2012)

Non-invasive diagnostic biomarkers for estimating the onset time of permanent cerebral ischemia
por: Berthet, Carole, et al.
Publicado: (2014)

The role of microglia and myeloid immune cells in acute cerebral ischemia
por: Benakis, Corinne, et al.
Publicado: (2015)

Caveolin-1 Regulates Perivascular Aquaporin-4 Expression After Cerebral Ischemia
por: Filchenko, Irina, et al.
Publicado: (2020)

Protease nexin-1 deficiency increases mouse hindlimb neovascularisation following ischemia and accelerates femoral artery perfusion
por: Selbonne, Sonia, et al.
Publicado: (2021)

Protease nexin-1 expression is altered in human breast cancer
por: Candia, Britny J, et al.
Publicado: (2006)

Protease Nexin-1 in the Cardiovascular System: Wherefore Art Thou?
por: Madjene, Celina, et al.
Publicado: (2021)

Novel ELISA for the specific detection of protease NEXIN‐1 in human biological samples
por: Venisse, Laurence, et al.
Publicado: (2022)

The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration
por: Wu, Xinghuo, et al.
Publicado: (2016)

The role of Serine Proteases and Serine Protease Inhibitors in the migration of Gonadotropin-Releasing Hormone neurons
por: Drapkin, Paola T, et al.
Publicado: (2002)

Protease nexin 1: a novel regulator of prostate cancer cell growth and neo-angiogenesis
por: McKee, Chad M., et al.
Publicado: (2013)

Sorting Nexins in Protein Homeostasis
por: Hanley, Sara E., et al.
Publicado: (2020)

Elevated Concentrations of SERPINE2/Protease Nexin-1 and Secretory Leukocyte Protease Inhibitor in the Serum of Patients with Papillary Thyroid Cancer
por: Stępień, Tomasz, et al.
Publicado: (2017)

Hydroxycarboxylic Acid Receptor 1 and Neuroprotection in a Mouse Model of Cerebral Ischemia-Reperfusion
por: Buscemi, Lara, et al.
Publicado: (2021)

Peter Cullen: Nexins have it sorted
por: Sedwick, Caitlin
Publicado: (2014)

Number of nexin links detectable at standard electron microscopy of normal human nasal cilia and at nexin link deficiency
por: Stenram, U, et al.
Publicado: (2015)

Protease nexin-1 prevents growth of human B cell lymphoma via inhibition of sonic hedgehog signaling
por: Xin, Xiangke, et al.
Publicado: (2018)

Immune mechanisms in cerebral ischemic tolerance
por: Garcia-Bonilla, Lidia, et al.
Publicado: (2014)

Newly generated cells are increased in hippocampus of adult mice lacking a serine protease inhibitor
por: Lino, Maddalena M, et al.
Publicado: (2010)

Phorbol ester and mitogens stimulate human fibroblast secretions of plasmin-activatable plasminogen activator and protease nexin, an antiactivator/antiplasmin
Publicado: (1983)

Overexpression of SerpinE2/protease nexin-1 Contribute to Pathological Cardiac Fibrosis via increasing Collagen Deposition
por: Li, Xuelian, et al.
Publicado: (2016)

The Retromer Complex and Sorting Nexins in Neurodegenerative Diseases
por: Zhang, Hongfeng, et al.
Publicado: (2018)

The emerging role of sorting nexins in cardiovascular diseases
por: Yang, Jian, et al.
Publicado: (2019)

The Role of Sorting Nexin 17 in Cardiac Development
por: Wu, Yufei, et al.
Publicado: (2021)

Protease nexin 1 induces apoptosis of prostate tumor cells through inhibition of X-chromosome-linked inhibitor of apoptosis protein
por: McKee, Chad M., et al.
Publicado: (2015)

An RGS-Containing Sorting Nexin Controls Drosophila Lifespan
por: Suh, Jae Myoung, et al.
Publicado: (2008)

Protease Nexin I is a feedback regulator of EGF/PKC/MAPK/EGR1 signaling in breast cancer cells metastasis and stemness
por: Tang, Tingting, et al.
Publicado: (2019)

A role for sorting nexin 27 in AMPA receptor trafficking
por: Loo, Li Shen, et al.
Publicado: (2014)

Detailed structural and biochemical characterization of the nexin-dynein regulatory complex
por: Oda, Toshiyuki, et al.
Publicado: (2015)

Sorting nexin-21 is a scaffold for the endosomal recruitment of huntingtin
por: Danson, Chris M., et al.
Publicado: (2018)

Sorting Nexin 9 facilitates podocin endocytosis in the injured podocyte
por: Sasaki, Yu, et al.
Publicado: (2017)

The endosomal protein sorting nexin 4 is a synaptic protein
por: Vazquez-Sanchez, Sonia, et al.
Publicado: (2020)

The emerging roles of retromer and sorting nexins in the life cycle of viruses
por: Lu, Yue, et al.
Publicado: (2022)

Sorting Nexin 5 Mediates Virus-Induced Autophagy and Immunity
por: Dong, Xiaonan, et al.
Publicado: (2020)

The Essential Role of Sorting Nexin 5 in Virus-Induced Autophagy
por: Li, Dong-Yi, et al.
Publicado: (2022)

Correction: Protease Nexin I is a feedback regulator of EGF/ PKC/MAPK/EGR1 signaling in breast cancer cells metastasis and stemness
por: Tang, Tingting, et al.
Publicado: (2020)

Lactate Neuroprotection against Transient Ischemic Brain Injury in Mice Appears Independent of HCAR1 Activation
por: Buscemi, Lara, et al.
Publicado: (2022)

Ubiquitin-Specific Protease 29 Exacerbates Cerebral Ischemia-Reperfusion Injury in Mice
por: Hou, Jia-Bao, et al.
Publicado: (2021)

Sorting nexin 27 interacts with Fzd7 and mediates Wnt signalling
por: Sun, Lixiang, et al.
Publicado: (2016)

Structural basis for the hijacking of endosomal sorting nexin proteins by Chlamydia trachomatis
por: Paul, Blessy, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_1a6614bhnjmf2hqdvfcvi1c6am