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ACE Inhibition with Captopril Retards the Development of Signs of Neurodegeneration in an Animal Model of Alzheimer’s Disease

Increased generation of reactive oxygen species (ROS) is a significant pathological feature in the brains of patients with Alzheimer’s disease (AD). Experimental evidence indicates that inhibition of brain ROS could be beneficial in slowing the neurodegenerative process triggered by amyloid-beta (Ab...

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Detalles Bibliográficos
Autores principales: AbdAlla, Said, Langer, Andreas, Fu, Xuebin, Quitterer, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759943/
https://www.ncbi.nlm.nih.gov/pubmed/23959119
http://dx.doi.org/10.3390/ijms140816917