Non-Coding RNAs and Cancer

The discovery of the biological relevance of non-coding RNA (ncRNAs) molecules represents one of the most significant advances in contemporary molecular biology. Expression profiling of human tumors, based on the expression of miRNAs and other short or long ncRNAs, has identified signatures associat...

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Detalles Bibliográficos
Autores principales: Calore, Federica, Lovat, Francesca, Garofalo, Michela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759953/
https://www.ncbi.nlm.nih.gov/pubmed/23965974
http://dx.doi.org/10.3390/ijms140817085
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author Calore, Federica
Lovat, Francesca
Garofalo, Michela
author_facet Calore, Federica
Lovat, Francesca
Garofalo, Michela
author_sort Calore, Federica
collection PubMed
description The discovery of the biological relevance of non-coding RNA (ncRNAs) molecules represents one of the most significant advances in contemporary molecular biology. Expression profiling of human tumors, based on the expression of miRNAs and other short or long ncRNAs, has identified signatures associated with diagnosis, staging, progression, prognosis, and response to treatment. In this review we will discuss the recent remarkable advancement in the understanding the biological functions of human ncRNAs in cancer, the mechanisms of expression and the therapeutic potential.
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spelling pubmed-37599532013-09-03 Non-Coding RNAs and Cancer Calore, Federica Lovat, Francesca Garofalo, Michela Int J Mol Sci Review The discovery of the biological relevance of non-coding RNA (ncRNAs) molecules represents one of the most significant advances in contemporary molecular biology. Expression profiling of human tumors, based on the expression of miRNAs and other short or long ncRNAs, has identified signatures associated with diagnosis, staging, progression, prognosis, and response to treatment. In this review we will discuss the recent remarkable advancement in the understanding the biological functions of human ncRNAs in cancer, the mechanisms of expression and the therapeutic potential. Molecular Diversity Preservation International (MDPI) 2013-08-19 /pmc/articles/PMC3759953/ /pubmed/23965974 http://dx.doi.org/10.3390/ijms140817085 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland http://creativecommons.org/licenses/by/3.0 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Calore, Federica
Lovat, Francesca
Garofalo, Michela
Non-Coding RNAs and Cancer
title Non-Coding RNAs and Cancer
title_full Non-Coding RNAs and Cancer
title_fullStr Non-Coding RNAs and Cancer
title_full_unstemmed Non-Coding RNAs and Cancer
title_short Non-Coding RNAs and Cancer
title_sort non-coding rnas and cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759953/
https://www.ncbi.nlm.nih.gov/pubmed/23965974
http://dx.doi.org/10.3390/ijms140817085
work_keys_str_mv AT calorefederica noncodingrnasandcancer
AT lovatfrancesca noncodingrnasandcancer
AT garofalomichela noncodingrnasandcancer

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