Molecular Interactions in the Development of Brain Metastases

Brain metastases are a much-feared complication of cancer. The development of brain metastases requires a malignant cell to acquire characteristics that facilitate dissemination away from the primary site, entrance into the nervous system, and establishment in the brain. This review summarizes recen...

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Detalles Bibliográficos
Autores principales: Martinez, Nina, Boire, Adrienne, DeAngelis, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759957/
https://www.ncbi.nlm.nih.gov/pubmed/23965978
http://dx.doi.org/10.3390/ijms140817157
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author Martinez, Nina
Boire, Adrienne
DeAngelis, Lisa M.
author_facet Martinez, Nina
Boire, Adrienne
DeAngelis, Lisa M.
author_sort Martinez, Nina
collection PubMed
description Brain metastases are a much-feared complication of cancer. The development of brain metastases requires a malignant cell to acquire characteristics that facilitate dissemination away from the primary site, entrance into the nervous system, and establishment in the brain. This review summarizes recent work focused on the molecular derangements leading to brain metastases and outlines areas in need of greater understanding.
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spelling pubmed-37599572013-09-03 Molecular Interactions in the Development of Brain Metastases Martinez, Nina Boire, Adrienne DeAngelis, Lisa M. Int J Mol Sci Review Brain metastases are a much-feared complication of cancer. The development of brain metastases requires a malignant cell to acquire characteristics that facilitate dissemination away from the primary site, entrance into the nervous system, and establishment in the brain. This review summarizes recent work focused on the molecular derangements leading to brain metastases and outlines areas in need of greater understanding. Molecular Diversity Preservation International (MDPI) 2013-08-20 /pmc/articles/PMC3759957/ /pubmed/23965978 http://dx.doi.org/10.3390/ijms140817157 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland http://creativecommons.org/licenses/by/3.0 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Martinez, Nina
Boire, Adrienne
DeAngelis, Lisa M.
Molecular Interactions in the Development of Brain Metastases
title Molecular Interactions in the Development of Brain Metastases
title_full Molecular Interactions in the Development of Brain Metastases
title_fullStr Molecular Interactions in the Development of Brain Metastases
title_full_unstemmed Molecular Interactions in the Development of Brain Metastases
title_short Molecular Interactions in the Development of Brain Metastases
title_sort molecular interactions in the development of brain metastases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759957/
https://www.ncbi.nlm.nih.gov/pubmed/23965978
http://dx.doi.org/10.3390/ijms140817157
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