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The shrimp IKK–NF-κB signaling pathway regulates antimicrobial peptide expression and may be subverted by white spot syndrome virus to facilitate viral gene expression

The IκB kinases IKKα and IKKβ and the IKK-related kinases TANK-binding kinase 1 (TBK1) and IKKε are the master regulators of the NF-κB signaling pathway. Although this pathway has been extensively studied in mammals, less attention has been paid in crustaceans, which have significant economic value....

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Detalles Bibliográficos
Autores principales: Wang, Pei-Hui, Gu, Zhi-Hua, Wan, Ding-Hui, Liu, Bo-Du, Huang, Xian-De, Weng, Shao-Ping, Yu, Xiao-Qiang, He, Jian-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759962/
https://www.ncbi.nlm.nih.gov/pubmed/23954949
http://dx.doi.org/10.1038/cmi.2013.30

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