Cargando…

Vibrio cholerae ToxR Downregulates Virulence Factor Production in Response to Cyclo(Phe-Pro)

Vibrio cholerae is an aquatic organism that causes the severe acute diarrheal disease cholera. The ability of V. cholerae to cause disease is dependent upon the production of two critical virulence determinants, cholera toxin (CT) and the toxin-coregulated pilus (TCP). The expression of the genes th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bina, X. Renee, Taylor, Dawn L., Vikram, Amit, Ante, Vanessa M., Bina, James E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760244/ https://www.ncbi.nlm.nih.gov/pubmed/23982069 http://dx.doi.org/10.1128/mBio.00366-13

Ejemplares similares

Vibrio cholerae’s ToxRS bile sensing system
por: Gubensäk, Nina, et al.
Publicado: (2023)

Virulence regulator AphB enhances toxR transcription in Vibrio cholerae
por: Xu, Xiao, et al.
Publicado: (2010)

Disulfide Bond Formation and ToxR Activity in Vibrio cholerae
por: Fengler, Vera H. I., et al.
Publicado: (2012)

Proteolysis of Virulence Regulator ToxR Is Associated with Entry of Vibrio cholerae into a Dormant State
por: Almagro-Moreno, Salvador, et al.
Publicado: (2015)

Vibrio cholerae CsrA Regulates ToxR Levels in Response to Amino Acids and Is Essential for Virulence
por: Mey, Alexandra R., et al.
Publicado: (2015)

ToxR of Vibrio cholerae affects biofilm, rugosity and survival with Acanthamoeba castellanii
por: Valeru, Soni P, et al.
Publicado: (2012)

Host stimuli and operator binding sites controlling protein interactions between virulence master regulator ToxR and ToxS in Vibrio cholerae
por: Lembke, Mareike, et al.
Publicado: (2020)

ToxR activates the Vibrio cholerae virulence genes by tethering DNA to the membrane through versatile binding to multiple sites
por: Canals, Albert, et al.
Publicado: (2023)

Toxin, toxin-coregulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans
Publicado: (1988)

Proteolysis of ToxR is controlled by cysteine‐thiol redox state and bile salts in Vibrio cholerae
por: Lembke, Mareike, et al.
Publicado: (2018)

Structural and DNA-binding properties of the cytoplasmic domain of Vibrio cholerae transcription factor ToxR
por: Gubensäk, Nina, et al.
Publicado: (2021)

Direct Binding and Regulation by Fur and HapR of the Intermediate Regulator and Virulence Factor Genes Within the ToxR Virulence Regulon in Vibrio cholerae
por: Gao, He, et al.
Publicado: (2020)

Autoregulation of ToxR and Its Regulatory Actions on Major Virulence Gene Loci in Vibrio parahaemolyticus
por: Zhang, Yiquan, et al.
Publicado: (2018)

The Vibrio cholerae RND efflux systems impact virulence factor production and adaptive responses via periplasmic sensor proteins
por: Bina, X. Renee, et al.
Publicado: (2018)

Substrate-Dependent Activation of the Vibrio cholerae vexAB RND Efflux System Requires vexR
por: Taylor, Dawn L., et al.
Publicado: (2015)

The periplasmic domains of Vibriocholerae ToxR and ToxS are forming a strong heterodimeric complex independent on the redox state of ToxR cysteines
por: Gubensäk, Nina, et al.
Publicado: (2021)

Cyclo-(l-Phe-l-Pro), a Quorum-Sensing Signal of Vibrio vulnificus, Induces Expression of Hydroperoxidase through a ToxR-LeuO-HU-RpoS Signaling Pathway To Confer Resistance against Oxidative Stress
por: Kim, In Hwang, et al.
Publicado: (2018)

Development of a toxR-based loop-mediated isothermal amplification assay for detecting Vibrio parahaemolyticus
por: Chen, Siyi, et al.
Publicado: (2010)

Vibrio cholerae RND efflux systems: mediators of stress responses, colonization and pathogenesis
por: Bina, X. Renee, et al.
Publicado: (2023)

Transcriptional Regulation of the Type VI Secretion System 1 Genes by Quorum Sensing and ToxR in Vibrio parahaemolyticus
por: Zhang, Yiquan, et al.
Publicado: (2017)

Regulatory actions of ToxR and CalR on their own genes and type III secretion system 1 in Vibrio parahaemolyticus
por: Osei-Adjei, George, et al.
Publicado: (2017)

Corrigendum: Transcriptional Regulation of the Type VI Secretion System 1 Genes by Quorum Sensing and ToxR in Vibrio parahaemolyticus
por: Zhang, Yiquan, et al.
Publicado: (2020)

Complete Genome Sequence of Vibrio cholerae O1 El Tor Strain C6706
por: Weng, Yuding, et al.
Publicado: (2021)

The complexity of ToxT-dependent transcription in Vibrio cholerae
por: Weber, Gregor G., et al.
Publicado: (2011)

Vibrio cholerae vexH Encodes a Multiple Drug Efflux Pump That Contributes to the Production of Cholera Toxin and the Toxin Co-Regulated Pilus
por: Taylor, Dawn L., et al.
Publicado: (2012)

The Vibrio cholerae VexGH RND Efflux System Maintains Cellular Homeostasis by Effluxing Vibriobactin
por: Kunkle, Dillon E., et al.
Publicado: (2017)

A disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts
por: Midgett, Charles R., et al.
Publicado: (2020)

Small-Molecule Inhibitors of toxT Expression in Vibrio cholerae
por: Anthouard, Rebecca, et al.
Publicado: (2013)

The wing of the ToxR winged helix-turn-helix domain is required for DNA binding and activation of toxT and ompU
por: Morgan, Sarah J., et al.
Publicado: (2019)

A new class of inhibitors of the AraC family virulence regulator Vibrio cholerae ToxT
por: Woodbrey, Anne K., et al.
Publicado: (2017)

DNA-binding directs the localization of a membrane-integrated receptor of the ToxR family
por: Brameyer, Sophie, et al.
Publicado: (2019)

Publisher Correction: A disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts
por: Midgett, Charles R., et al.
Publicado: (2020)

Vibrio vulnificus induces the death of a major bacterial species in the mouse gut via cyclo-Phe-Pro
por: Kim, Jeong-A, et al.
Publicado: (2021)

Iron-Fur complex suppresses the expression of components of the cyclo-(Phe-Pro)-signaling regulatory pathway in Vibrio vulnificus
por: Lee, Keun-Woo, et al.
Publicado: (2023)

Unambiguous Stereochemical Assignment of Cyclo(Phe-Pro), Cyclo(Leu-Pro), and Cyclo(Val-Pro) by Electronic Circular Dichroic Spectroscopy
por: Domzalski, Alison, et al.
Publicado: (2021)

ToxR Antagonizes H-NS Regulation of Horizontally Acquired Genes to Drive Host Colonization
por: Kazi, Misha I., et al.
Publicado: (2016)

Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity
por: Lee, Wooseong, et al.
Publicado: (2018)

Structural and Biofunctional Insights into the Cyclo(Pro-Pro-Phe-Phe-) Scaffold from Experimental and In Silico Studies: Melanoma and Beyond †
por: Bojarska, Joanna, et al.
Publicado: (2022)

Molecular dynamics simulation (MDS) analysis of Vibrio cholerae ToxT virulence factor complexed with docked potential inhibitors
por: Torktaz, Ibrahim, et al.
Publicado: (2018)

Independent Promoter Recognition by TcpP Precedes Cooperative Promoter Activation by TcpP and ToxR
por: Calkins, A. L., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jcgd5l2qk057rmu2dcuhac9vc2