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Mimicking Protein–Protein Interactions through Peptide–Peptide Interactions: HIV-1 gp120 and CXCR4

We have recently designed a soluble synthetic peptide that functionally mimics the HIV-1 coreceptor CXCR4, which is a chemokine receptor that belongs to the family of seven-transmembrane GPCRs. This CXCR4 mimetic peptide, termed CX4-M1, presents the three extracellular loops (ECLs) of the receptor....

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Detalles Bibliográficos
Autores principales:	Groß, Andrea, Möbius, Kalle, Haußner, Christina, Donhauser, Norbert, Schmidt, Barbara, Eichler, Jutta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760305/ https://www.ncbi.nlm.nih.gov/pubmed/24027570 http://dx.doi.org/10.3389/fimmu.2013.00257

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