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Association of CYP3A4/5, ABCB1 and ABCC2 polymorphisms and clinical outcomes of Thai breast cancer patients treated with tamoxifen

BACKGROUND: Pharmacogenetic study of cytochrome P450 (CYP) gene CYP2D6 and tamoxifen outcomes remain controversial. Apart from CYP2D6, other drug-metabolizing enzymes and transporters also play a role in tamoxifen metabolic pathways. The aim of this study is to investigate the impact of CYP3A4/5, AB...

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Detalles Bibliográficos
Autores principales:	Sensorn, Insee, Sirachainan, Ekaphop, Chamnanphon, Montri, Pasomsub, Ekawat, Trachu, Narumol, Supavilai, Porntip, Sukasem, Chonlaphat, Pinthong, Darawan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760448/ https://www.ncbi.nlm.nih.gov/pubmed/24019753 http://dx.doi.org/10.2147/PGPM.S44006

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