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Distinct signaling mechanisms regulate migration in unconfined versus confined spaces

Using a microchannel assay, we demonstrate that cells adopt distinct signaling strategies to modulate cell migration in different physical microenvironments. We studied α4β1 integrin–mediated signaling, which regulates cell migration pertinent to embryonic development, leukocyte trafficking, and mel...

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Detalles Bibliográficos
Autores principales:	Hung, Wei-Chien, Chen, Shih-Hsun, Paul, Colin D., Stroka, Kimberly M., Lo, Ying-Chun, Yang, Joy T., Konstantopoulos, Konstantinos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760608/ https://www.ncbi.nlm.nih.gov/pubmed/23979717 http://dx.doi.org/10.1083/jcb.201302132

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