FGF-23 Regulates CYP27B1 Transcription in the Kidney and in Extra-Renal Tissues

The mitochondrial enzyme 25-hydroxyvitamin D 1α-hydroxylase, which is encoded by the CYP27B1 gene, converts 25OHD to the biological active form of vitamin D, 1,25-dihydroxyvitamin D (1,25(OH)(2)D). Renal 1α-hydroxylase activity is the principal determinant of the circulating 1,25(OH)(2)D concentrati...

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Detalles Bibliográficos
Autores principales: Chanakul, Ankanee, Zhang, Martin Y. H., Louw, Andrew, Armbrecht, Harvey J., Miller, Walter L., Portale, Anthony A., Perwad, Farzana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760837/
https://www.ncbi.nlm.nih.gov/pubmed/24019880
http://dx.doi.org/10.1371/journal.pone.0072816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760837/
https://www.ncbi.nlm.nih.gov/pubmed/24019880
http://dx.doi.org/10.1371/journal.pone.0072816

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