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FGF-23 Regulates CYP27B1 Transcription in the Kidney and in Extra-Renal Tissues
The mitochondrial enzyme 25-hydroxyvitamin D 1α-hydroxylase, which is encoded by the CYP27B1 gene, converts 25OHD to the biological active form of vitamin D, 1,25-dihydroxyvitamin D (1,25(OH)(2)D). Renal 1α-hydroxylase activity is the principal determinant of the circulating 1,25(OH)(2)D concentrati...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760837/ https://www.ncbi.nlm.nih.gov/pubmed/24019880 http://dx.doi.org/10.1371/journal.pone.0072816 |