AutomiG, a Biosensor to Detect Alterations in miRNA Biogenesis and in Small RNA Silencing Guided by Perfect Target Complementarity

Defects in miRNA biogenesis or activity are associated to development abnormalities and diseases. In Drosophila, miRNAs are predominantly loaded in Argonaute-1, which they guide for silencing of target RNAs. The miRNA pathway overlaps the RNAi pathway in this organism, as miRNAs may also associate w...

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Detalles Bibliográficos
Autores principales: Carré, Clément, Jacquier, Caroline, Bougé, Anne-Laure, de Chaumont, Fabrice, Besnard-Guerin, Corinne, Thomassin, Hélène, Pidoux, Josette, Da Silva, Bruno, Chalatsi, Eleftheria, Zahra, Sarah, Olivo-Marin, Jean-Christophe, Munier-Lehmann, Hélène, Antoniewski, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760873/
https://www.ncbi.nlm.nih.gov/pubmed/24019960
http://dx.doi.org/10.1371/journal.pone.0074296

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