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p21-Activated Kinase (PAK) Regulates Cytoskeletal Reorganization and Directional Migration in Human Neutrophils

Neutrophils serve as a first line of defense in innate immunity owing in part to their ability to rapidly migrate towards chemotactic factors derived from invading pathogens. As a migratory function, neutrophil chemotaxis is regulated by the Rho family of small GTPases. However, the mechanisms by wh...

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Detalles Bibliográficos
Autores principales:	Itakura, Asako, Aslan, Joseph E., Kusanto, Branden T., Phillips, Kevin G., Porter, Juliana E., Newton, Paul K., Nan, Xiaolin, Insall, Robert H., Chernoff, Jonathan, McCarty, Owen J. T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760889/ https://www.ncbi.nlm.nih.gov/pubmed/24019894 http://dx.doi.org/10.1371/journal.pone.0073063

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