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Tie2-dependent VHL knockdown promotes airway microvascular regeneration and attenuates invasive growth of Aspergillus fumigatus

ABSTRACT: Microvascular ischemia and infections are associated with the development of chronic rejection following lung transplantation. The von Hippel–Lindau protein (VHL) controls protein levels of hypoxia-inducible factors (HIFs), regulates vascular repair, and improves tissue perfusion. Here, we...

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Detalles Bibliográficos
Autores principales: Jiang, Xinguo, Hsu, Joe L., Tian, Wen, Yuan, Ke, Olcholski, Mark, de Jesus Perez, Vinicio, Semenza, Gregg L., Nicolls, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3761091/
https://www.ncbi.nlm.nih.gov/pubmed/23797537
http://dx.doi.org/10.1007/s00109-013-1063-8