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BLM SUMOylation regulates ssDNA accumulation at stalled replication forks

Polymerase stalling results in uncoupling of DNA polymerase and the replicative helicase, which generates single-stranded DNA (ssDNA). After stalling, RAD51 accumulates at stalled replication forks to stabilize the fork and to repair by homologous recombination (HR) double-strand breaks (DSBs) that...

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Detalles Bibliográficos
Autores principales:	Ouyang, Karen J., Yagle, Mary K., Matunis, Michael J., Ellis, Nathan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3761158/ https://www.ncbi.nlm.nih.gov/pubmed/24027577 http://dx.doi.org/10.3389/fgene.2013.00167

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