Genotypic variation and outcomes in kidney transplantation: donor and recipient effects

The genetic composition of a donor impacts long term allograft survival after kidney transplantation. Effects of the recipient’s genetic make-up, particularly variation in immune response pathway genes are less certain. A report in this issue of Kidney International reveals improved graft survival i...

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Autores principales: Gautreaux, Michael D., Freedman, Barry I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3761401/
https://www.ncbi.nlm.nih.gov/pubmed/23989355
http://dx.doi.org/10.1038/ki.2013.167
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author Gautreaux, Michael D.
Freedman, Barry I.
author_facet Gautreaux, Michael D.
Freedman, Barry I.
author_sort Gautreaux, Michael D.
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description The genetic composition of a donor impacts long term allograft survival after kidney transplantation. Effects of the recipient’s genetic make-up, particularly variation in immune response pathway genes are less certain. A report in this issue of Kidney International reveals improved graft survival in transplant recipients with lower copy numbers of the complement 4 gene (C4) after receipt of deceased donor kidneys. Genomics breakthroughs in nephrology and immunology will likely revolutionize the field of transplant medicine.
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spelling pubmed-37614012014-03-01 Genotypic variation and outcomes in kidney transplantation: donor and recipient effects Gautreaux, Michael D. Freedman, Barry I. Kidney Int Article The genetic composition of a donor impacts long term allograft survival after kidney transplantation. Effects of the recipient’s genetic make-up, particularly variation in immune response pathway genes are less certain. A report in this issue of Kidney International reveals improved graft survival in transplant recipients with lower copy numbers of the complement 4 gene (C4) after receipt of deceased donor kidneys. Genomics breakthroughs in nephrology and immunology will likely revolutionize the field of transplant medicine. 2013-09 /pmc/articles/PMC3761401/ /pubmed/23989355 http://dx.doi.org/10.1038/ki.2013.167 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Gautreaux, Michael D.
Freedman, Barry I.
Genotypic variation and outcomes in kidney transplantation: donor and recipient effects
title Genotypic variation and outcomes in kidney transplantation: donor and recipient effects
title_full Genotypic variation and outcomes in kidney transplantation: donor and recipient effects
title_fullStr Genotypic variation and outcomes in kidney transplantation: donor and recipient effects
title_full_unstemmed Genotypic variation and outcomes in kidney transplantation: donor and recipient effects
title_short Genotypic variation and outcomes in kidney transplantation: donor and recipient effects
title_sort genotypic variation and outcomes in kidney transplantation: donor and recipient effects
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3761401/
https://www.ncbi.nlm.nih.gov/pubmed/23989355
http://dx.doi.org/10.1038/ki.2013.167
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