Serum Level of Ghrelin in Umbilical Cord in Small and Appropriate for Gestational Age Newborn Infants and its Relationship to Anthropometric Measures

OBJECTIVE: To compare the cord blood ghrelin level in (SGA) infants with the level in appropriate for gestational age (AGA) infants, and determine its relationship to anthropometric measurements at delivery. MATERIALS AND METHODS: Fifty newborn infants (30 SGA newborns and 20 AGA infants) were inclu...

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Autores principales: Abdel Hakeem, Abdel Hakeem A., Saed, Samera Z., El Rehany, Mahmoud A., Yassin, Essam E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762029/
https://www.ncbi.nlm.nih.gov/pubmed/24027709
http://dx.doi.org/10.4103/2249-4847.101694
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author Abdel Hakeem, Abdel Hakeem A.
Saed, Samera Z.
El Rehany, Mahmoud A.
Yassin, Essam E.
author_facet Abdel Hakeem, Abdel Hakeem A.
Saed, Samera Z.
El Rehany, Mahmoud A.
Yassin, Essam E.
author_sort Abdel Hakeem, Abdel Hakeem A.
collection PubMed
description OBJECTIVE: To compare the cord blood ghrelin level in (SGA) infants with the level in appropriate for gestational age (AGA) infants, and determine its relationship to anthropometric measurements at delivery. MATERIALS AND METHODS: Fifty newborn infants (30 SGA newborns and 20 AGA infants) were included in the study and were subjected to complete clinical examinations, anthropometric measurement, and ghrelin assays. RESULTS: The cord blood ghrelin level in SGA infants was significantly higher than that in AGA infants. Cord ghrelin level correlated negatively with gestational age, weight, length, and body mass index in SGA group. CONCLUSION: Cord ghrelin concentration increased in SGA infants due to state of prolonged undernutrition the source of ghrelin unknown may be from the mother placenta or fetal tissues.
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spelling pubmed-37620292013-09-11 Serum Level of Ghrelin in Umbilical Cord in Small and Appropriate for Gestational Age Newborn Infants and its Relationship to Anthropometric Measures Abdel Hakeem, Abdel Hakeem A. Saed, Samera Z. El Rehany, Mahmoud A. Yassin, Essam E. J Clin Neonatol Original Article OBJECTIVE: To compare the cord blood ghrelin level in (SGA) infants with the level in appropriate for gestational age (AGA) infants, and determine its relationship to anthropometric measurements at delivery. MATERIALS AND METHODS: Fifty newborn infants (30 SGA newborns and 20 AGA infants) were included in the study and were subjected to complete clinical examinations, anthropometric measurement, and ghrelin assays. RESULTS: The cord blood ghrelin level in SGA infants was significantly higher than that in AGA infants. Cord ghrelin level correlated negatively with gestational age, weight, length, and body mass index in SGA group. CONCLUSION: Cord ghrelin concentration increased in SGA infants due to state of prolonged undernutrition the source of ghrelin unknown may be from the mother placenta or fetal tissues. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3762029/ /pubmed/24027709 http://dx.doi.org/10.4103/2249-4847.101694 Text en Copyright: © Journal of Clinical Neonatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Abdel Hakeem, Abdel Hakeem A.
Saed, Samera Z.
El Rehany, Mahmoud A.
Yassin, Essam E.
Serum Level of Ghrelin in Umbilical Cord in Small and Appropriate for Gestational Age Newborn Infants and its Relationship to Anthropometric Measures
title Serum Level of Ghrelin in Umbilical Cord in Small and Appropriate for Gestational Age Newborn Infants and its Relationship to Anthropometric Measures
title_full Serum Level of Ghrelin in Umbilical Cord in Small and Appropriate for Gestational Age Newborn Infants and its Relationship to Anthropometric Measures
title_fullStr Serum Level of Ghrelin in Umbilical Cord in Small and Appropriate for Gestational Age Newborn Infants and its Relationship to Anthropometric Measures
title_full_unstemmed Serum Level of Ghrelin in Umbilical Cord in Small and Appropriate for Gestational Age Newborn Infants and its Relationship to Anthropometric Measures
title_short Serum Level of Ghrelin in Umbilical Cord in Small and Appropriate for Gestational Age Newborn Infants and its Relationship to Anthropometric Measures
title_sort serum level of ghrelin in umbilical cord in small and appropriate for gestational age newborn infants and its relationship to anthropometric measures
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762029/
https://www.ncbi.nlm.nih.gov/pubmed/24027709
http://dx.doi.org/10.4103/2249-4847.101694
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