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Cytosolic Ca(2+) shifts as early markers of cytotoxicity

The determination of the cytotoxic potential of new and so far unknown compounds as well as their metabolites is fundamental in risk assessment. A variety of strategic endpoints have been defined to describe toxin-cell interactions, leading to prediction of cell fate. They involve measurement of met...

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Detalles Bibliográficos
Autores principales: Wyrsch, Philippe, Blenn, Christian, Pesch, Theresa, Beneke, Sascha, Althaus, Felix R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762065/
https://www.ncbi.nlm.nih.gov/pubmed/23384168
http://dx.doi.org/10.1186/1478-811X-11-11