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Cytosolic Ca(2+) shifts as early markers of cytotoxicity
The determination of the cytotoxic potential of new and so far unknown compounds as well as their metabolites is fundamental in risk assessment. A variety of strategic endpoints have been defined to describe toxin-cell interactions, leading to prediction of cell fate. They involve measurement of met...
Autores principales: | Wyrsch, Philippe, Blenn, Christian, Pesch, Theresa, Beneke, Sascha, Althaus, Felix R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762065/ https://www.ncbi.nlm.nih.gov/pubmed/23384168 http://dx.doi.org/10.1186/1478-811X-11-11 |
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