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The Flavin-Containing Reductase Domain of Cytochrome P450 BM3 Acts as a Surrogate for Mammalian NADPH-P450 Reductase

Cytochrome P450 BM3 (CYP102A1) from Bacillus megaterium is a self-sufficient monooxygenase that consists of a heme domain and FAD/FMN-containing reductase domain (BMR). In this report, the reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and 5-cyano-2,3-ditolyl tetrazo...

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Detalles Bibliográficos
Autores principales: Park, Seon-Ha, Kang, Ji-Yeon, Kim, Dong-Hyun, Ahn, Taeho, Yun, Chul-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762289/
https://www.ncbi.nlm.nih.gov/pubmed/24009851
http://dx.doi.org/10.4062/biomolther.2012.20.6.562

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