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Three-color single molecule imaging shows WASP detachment from Arp2/3 complex triggers actin filament branch formation
During cell locomotion and endocytosis, membrane-tethered WASP proteins stimulate actin filament nucleation by the Arp2/3 complex. This process generates highly branched arrays of filaments that grow toward the membrane to which they are tethered, a conflict that seemingly would restrict filament gr...
Autores principales: | Smith, Benjamin A, Padrick, Shae B, Doolittle, Lynda K, Daugherty-Clarke, Karen, Corrêa, Ivan R, Xu, Ming-Qun, Goode, Bruce L, Rosen, Michael K, Gelles, Jeff |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762362/ https://www.ncbi.nlm.nih.gov/pubmed/24015360 http://dx.doi.org/10.7554/eLife.01008 |
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