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Pseudophosphorylated αB-Crystallin Is a Nuclear Chaperone Imported into the Nucleus with Help of the SMN Complex
The human small heat shock protein αB-crystallin (HspB5) is a molecular chaperone which is mainly localized in the cytoplasm. A small fraction can also be found in nuclear speckles, of which the localization is mediated by successional phosphorylation at Ser-59 and Ser-45. αB-crystallin does not con...
Autores principales: | den Engelsman, John, van de Schootbrugge, Chantal, Yong, Jeongsik, Pruijn, Ger J. M., Boelens, Wilbert C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762725/ https://www.ncbi.nlm.nih.gov/pubmed/24023879 http://dx.doi.org/10.1371/journal.pone.0073489 |
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