Cargando…
Androgen Receptor Function Links Human Sexual Dimorphism to DNA Methylation
Sex differences are well known to be determinants of development, health and disease. Epigenetic mechanisms are also known to differ between men and women through X-inactivation in females. We hypothesized that epigenetic sex differences may also result from sex hormone functions, in particular from...
Autores principales: | Ammerpohl, Ole, Bens, Susanne, Appari, Mahesh, Werner, Ralf, Korn, Bernhard, Drop, Stenvert L. S., Verheijen, Frans, van der Zwan, Yvonne, Bunch, Trevor, Hughes, Ieuan, Cools, Martine, Riepe, Felix G., Hiort, Olaf, Siebert, Reiner, Holterhus, Paul-Martin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762730/ https://www.ncbi.nlm.nih.gov/pubmed/24023855 http://dx.doi.org/10.1371/journal.pone.0073288 |
Ejemplares similares
-
Disorders of sex development expose transcriptional autonomy of genetic sex and androgen-programmed hormonal sex in human blood leukocytes
por: Holterhus, Paul-Martin, et al.
Publicado: (2009) -
A Recurrent Germline Mutation in the 5’UTR of the Androgen Receptor Causes Complete Androgen Insensitivity by Activating Aberrant uORF Translation
por: Hornig, Nadine C., et al.
Publicado: (2016) -
In vivo Investigations of the Effect of Short- and Long-Term Recombinant Growth Hormone Treatment on DNA-Methylation in Humans
por: Kolarova, Julia, et al.
Publicado: (2015) -
Intrinsic androgen-dependent gene expression patterns revealed by comparison of genital fibroblasts from normal males and individuals with complete and partial androgen insensitivity syndrome
por: Holterhus, Paul-Martin, et al.
Publicado: (2007) -
Differential gene-expression patterns in genital fibroblasts of normal males and 46,XY females with androgen insensitivity syndrome: evidence for early programming involving the androgen receptor
por: Holterhus, Paul-Martin, et al.
Publicado: (2003)