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Clinical implications of antitelomeric drugs with respect to the nontelomeric functions of telomerase in cancer
Telomerase is responsible for maintaining the length of telomeres at the ends of chromosomes. Although most somatic cells do not exhibit telomerase activity, it is reactivated in approximately 85% of cancers. This simple and attractive phenomenon steers the development of anticancer drugs targeting...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762763/ https://www.ncbi.nlm.nih.gov/pubmed/24009427 http://dx.doi.org/10.2147/OTT.S50918 |