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Rehydration Capacities and Rates for Various Porcine Tissues after Dehydration
The biphasic effects of liquid on tissue biomechanics are well known in cartilage and vocal folds, yet not extensively in other tissue types. Past studies have shown that tissue dehydration significantly impacts biomechanical properties and that rehydration can restore these properties in certain ti...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762799/ https://www.ncbi.nlm.nih.gov/pubmed/24023753 http://dx.doi.org/10.1371/journal.pone.0072573 |
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author | Meyer, Jacob P. McAvoy, Kieran E. Jiang, Jack |
author_facet | Meyer, Jacob P. McAvoy, Kieran E. Jiang, Jack |
author_sort | Meyer, Jacob P. |
collection | PubMed |
description | The biphasic effects of liquid on tissue biomechanics are well known in cartilage and vocal folds, yet not extensively in other tissue types. Past studies have shown that tissue dehydration significantly impacts biomechanical properties and that rehydration can restore these properties in certain tissue types. However, these studies failed to consider how temporal exposure to dehydrating or rehydrating agents may alter tissue rehydration capacity, as overexposure to dehydration may permanently prevent rehydration to the initial liquid volume. Select porcine tissues were dehydrated until they reached between 100% and 40% of their initial mass. Each sample was allowed to rehydrate for 5 hours in a 0.9% saline solution, and the percent change between the initial and rehydrated mass values was calculated. Spearman correlation tests indicated a greater loss in mass despite rehydration when tissues were previously exposed to greater levels of dehydration. Additionally, Pearson correlation tests indicated the total liquid mass of samples after complete rehydration decreased when previously exposed to higher levels of dehydration. Rehydration rates were found by dehydrating tissues to 40% of their initial mass followed by rehydration in a 0.9% saline solution for 60 minutes, with mass measurements occurring in 15 minute intervals. All tissues rehydrated nonlinearly, most increasing significantly in mass up to 30 minutes after initial soaking. This study suggests the ability for tissues to rehydrate is dependent on the level of initial dehydration exposure. In vitro rehydration experiments therefore require controlled dosage and temporal exposure to dehydrating and rehydrating agents to avoid incomplete rehydration, and caution should be taken when combining different tissue types in models of hydration. |
format | Online Article Text |
id | pubmed-3762799 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-37627992013-09-10 Rehydration Capacities and Rates for Various Porcine Tissues after Dehydration Meyer, Jacob P. McAvoy, Kieran E. Jiang, Jack PLoS One Research Article The biphasic effects of liquid on tissue biomechanics are well known in cartilage and vocal folds, yet not extensively in other tissue types. Past studies have shown that tissue dehydration significantly impacts biomechanical properties and that rehydration can restore these properties in certain tissue types. However, these studies failed to consider how temporal exposure to dehydrating or rehydrating agents may alter tissue rehydration capacity, as overexposure to dehydration may permanently prevent rehydration to the initial liquid volume. Select porcine tissues were dehydrated until they reached between 100% and 40% of their initial mass. Each sample was allowed to rehydrate for 5 hours in a 0.9% saline solution, and the percent change between the initial and rehydrated mass values was calculated. Spearman correlation tests indicated a greater loss in mass despite rehydration when tissues were previously exposed to greater levels of dehydration. Additionally, Pearson correlation tests indicated the total liquid mass of samples after complete rehydration decreased when previously exposed to higher levels of dehydration. Rehydration rates were found by dehydrating tissues to 40% of their initial mass followed by rehydration in a 0.9% saline solution for 60 minutes, with mass measurements occurring in 15 minute intervals. All tissues rehydrated nonlinearly, most increasing significantly in mass up to 30 minutes after initial soaking. This study suggests the ability for tissues to rehydrate is dependent on the level of initial dehydration exposure. In vitro rehydration experiments therefore require controlled dosage and temporal exposure to dehydrating and rehydrating agents to avoid incomplete rehydration, and caution should be taken when combining different tissue types in models of hydration. Public Library of Science 2013-09-04 /pmc/articles/PMC3762799/ /pubmed/24023753 http://dx.doi.org/10.1371/journal.pone.0072573 Text en © 2013 Meyer et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Meyer, Jacob P. McAvoy, Kieran E. Jiang, Jack Rehydration Capacities and Rates for Various Porcine Tissues after Dehydration |
title | Rehydration Capacities and Rates for Various Porcine Tissues after Dehydration |
title_full | Rehydration Capacities and Rates for Various Porcine Tissues after Dehydration |
title_fullStr | Rehydration Capacities and Rates for Various Porcine Tissues after Dehydration |
title_full_unstemmed | Rehydration Capacities and Rates for Various Porcine Tissues after Dehydration |
title_short | Rehydration Capacities and Rates for Various Porcine Tissues after Dehydration |
title_sort | rehydration capacities and rates for various porcine tissues after dehydration |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762799/ https://www.ncbi.nlm.nih.gov/pubmed/24023753 http://dx.doi.org/10.1371/journal.pone.0072573 |
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