Therapeutic Targeting of Tumor Growth and Angiogenesis with a Novel Anti-S100A4 Monoclonal Antibody

S100A4, a member of the S100 calcium-binding protein family secreted by tumor and stromal cells, supports tumorigenesis by stimulating angiogenesis. We demonstrated that S100A4 synergizes with vascular endothelial growth factor (VEGF), via the RAGE receptor, in promoting endothelial cell migration b...

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Detalles Bibliográficos
Autores principales: Hernández, Jose Luis, Padilla, Laura, Dakhel, Sheila, Coll, Toni, Hervas, Rosa, Adan, Jaume, Masa, Marc, Mitjans, Francesc, Martinez, Josep Maria, Coma, Silvia, Rodríguez, Laura, Noé, Véronique, Ciudad, Carlos J., Blasco, Francesc, Messeguer, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762817/
https://www.ncbi.nlm.nih.gov/pubmed/24023743
http://dx.doi.org/10.1371/journal.pone.0072480

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