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Therapeutic Targeting of Tumor Growth and Angiogenesis with a Novel Anti-S100A4 Monoclonal Antibody
S100A4, a member of the S100 calcium-binding protein family secreted by tumor and stromal cells, supports tumorigenesis by stimulating angiogenesis. We demonstrated that S100A4 synergizes with vascular endothelial growth factor (VEGF), via the RAGE receptor, in promoting endothelial cell migration b...
Autores principales: | Hernández, Jose Luis, Padilla, Laura, Dakhel, Sheila, Coll, Toni, Hervas, Rosa, Adan, Jaume, Masa, Marc, Mitjans, Francesc, Martinez, Josep Maria, Coma, Silvia, Rodríguez, Laura, Noé, Véronique, Ciudad, Carlos J., Blasco, Francesc, Messeguer, Ramon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762817/ https://www.ncbi.nlm.nih.gov/pubmed/24023743 http://dx.doi.org/10.1371/journal.pone.0072480 |
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