Post-Zygotic and Inter-Individual Structural Genetic Variation in a Presumptive Enhancer Element of the Locus between the IL10Rβ and IFNAR1 Genes

Although historically considered as junk-DNA, tandemly repeated sequence motifs can affect human phenotype. For example, variable number tandem repeats (VNTR) with embedded enhancers have been shown to regulate gene transcription. The post-zygotic variation is the presence of genetically distinct po...

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Detalles Bibliográficos
Autores principales: Razzaghian, Hamid Reza, Forsberg, Lars A., Prakash, Kancherla Reddy, Przerada, Szymon, Paprocka, Hanna, Zywicka, Anna, Westerman, Maxwell P., Pedersen, Nancy L., O'Hanlon, Terrance P., Rider, Lisa G., Miller, Frederick W., Srutek, Ewa, Jankowski, Michal, Zegarski, Wojciech, Piotrowski, Arkadiusz, Absher, Devin, Dumanski, Jan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762855/
https://www.ncbi.nlm.nih.gov/pubmed/24023707
http://dx.doi.org/10.1371/journal.pone.0067752

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