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Dynamics of DNA Damage Induced Pathways to Cancer

Chemotherapy is commonly used in cancer treatments, however only 25% of cancers are responsive and a significant proportion develops resistance. The p53 tumour suppressor is crucial for cancer development and therapy, but has been less amenable to therapeutic applications due to the complexity of it...

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Detalles Bibliográficos
Autores principales: Tian, Kun, Rajendran, Ramkumar, Doddananjaiah, Manjula, Krstic-Demonacos, Marija, Schwartz, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762865/
https://www.ncbi.nlm.nih.gov/pubmed/24023735
http://dx.doi.org/10.1371/journal.pone.0072303