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Dynamics of DNA Damage Induced Pathways to Cancer
Chemotherapy is commonly used in cancer treatments, however only 25% of cancers are responsive and a significant proportion develops resistance. The p53 tumour suppressor is crucial for cancer development and therapy, but has been less amenable to therapeutic applications due to the complexity of it...
Autores principales: | Tian, Kun, Rajendran, Ramkumar, Doddananjaiah, Manjula, Krstic-Demonacos, Marija, Schwartz, Jean-Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762865/ https://www.ncbi.nlm.nih.gov/pubmed/24023735 http://dx.doi.org/10.1371/journal.pone.0072303 |
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