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Architecture and DNA Recognition Elements of the Fanconi Anemia FANCM-FAAP24 Complex

Fanconi anemia (FA) is a disorder associated with a failure in DNA repair. FANCM (defective in FA complementation group M) and its partner FAAP24 target other FA proteins to sites of DNA damage. FANCM-FAAP24 is related to XPF/MUS81 endonucleases but lacks endonucleolytic activity. We report a struct...

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Detalles Bibliográficos
Autores principales:	Coulthard, Rachel, Deans, Andrew J., Swuec, Paolo, Bowles, Maureen, Costa, Alessandro, West, Stephen C., McDonald, Neil Q.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763369/ https://www.ncbi.nlm.nih.gov/pubmed/23932590 http://dx.doi.org/10.1016/j.str.2013.07.006

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