Changes in Ect2 Localization Couple Actomyosin-Dependent Cell Shape Changes to Mitotic Progression

As they enter mitosis, animal cells undergo profound actin-dependent changes in shape to become round. Here we identify the Cdk1 substrate, Ect2, as a central regulator of mitotic rounding, thus uncovering a link between the cell-cycle machinery that drives mitotic entry and its accompanying actin r...

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Detalles Bibliográficos
Autores principales: Matthews, Helen K., Delabre, Ulysse, Rohn, Jennifer L., Guck, Jochen, Kunda, Patricia, Baum, Buzz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763371/
https://www.ncbi.nlm.nih.gov/pubmed/22898780
http://dx.doi.org/10.1016/j.devcel.2012.06.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763371/
https://www.ncbi.nlm.nih.gov/pubmed/22898780
http://dx.doi.org/10.1016/j.devcel.2012.06.003

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