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Changes in Ect2 Localization Couple Actomyosin-Dependent Cell Shape Changes to Mitotic Progression

As they enter mitosis, animal cells undergo profound actin-dependent changes in shape to become round. Here we identify the Cdk1 substrate, Ect2, as a central regulator of mitotic rounding, thus uncovering a link between the cell-cycle machinery that drives mitotic entry and its accompanying actin r...

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Detalles Bibliográficos
Autores principales:	Matthews, Helen K., Delabre, Ulysse, Rohn, Jennifer L., Guck, Jochen, Kunda, Patricia, Baum, Buzz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763371/ https://www.ncbi.nlm.nih.gov/pubmed/22898780 http://dx.doi.org/10.1016/j.devcel.2012.06.003

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