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Cellular-Level Versus Receptor-Level Response Threshold Hierarchies in T-Cell Activation

Peptide-MHC (pMHC) ligand engagement by T-cell receptors (TCRs) elicits a variety of cellular responses, some of which require substantially more TCR-mediated stimulation than others. This threshold hierarchy could reside at the receptor level, where different response pathways branch off at differe...

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Detalles Bibliográficos
Autores principales:	van den Berg, Hugo A., Ladell, Kristin, Miners, Kelly, Laugel, Bruno, Llewellyn-Lacey, Sian, Clement, Mathew, Cole, David K., Gostick, Emma, Wooldridge, Linda, Sewell, Andrew K., Bridgeman, John S., Price, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763380/ https://www.ncbi.nlm.nih.gov/pubmed/24046768 http://dx.doi.org/10.3389/fimmu.2013.00250

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