KPNA2 promotes cell proliferation and tumorigenicity in epithelial ovarian carcinoma through upregulation of c-Myc and downregulation of FOXO3a

Karyopherin alpha 2 (KPNA2), a member of the karyopherin family, has a central role in nucleocytoplasmic transport and is overexpressed in many cancers. Our previous study identified KPNA2 as significantly upregulated in epithelial ovarian carcinoma (EOC), correlating with poor survival of patients....

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Detalles Bibliográficos
Autores principales: Huang, L, Wang, H-Y, Li, J-D, Wang, J-H, Zhou, Y, Luo, R-Z, Yun, J-P, Zhang, Y, Jia, W-H, Zheng, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763430/
https://www.ncbi.nlm.nih.gov/pubmed/23907459
http://dx.doi.org/10.1038/cddis.2013.256

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