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Selective GPER activation decreases proliferation and activates apoptosis in tumor Leydig cells
We have previously shown that estrogens binding to estrogen receptor (ER) α increase proliferation of Leydig tumor cells. Estrogens can also bind to G protein-coupled ER (GPER) and activation of this receptor can either increase or decrease cell proliferation of several tumor types. The aim of this...
Autores principales: | Chimento, A, Casaburi, I, Bartucci, M, Patrizii, M, Dattilo, R, Avena, P, Andò, S, Pezzi, V, Sirianni, R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763437/ https://www.ncbi.nlm.nih.gov/pubmed/23907461 http://dx.doi.org/10.1038/cddis.2013.275 |
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