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GADD34 induces cell death through inactivation of Akt following traumatic brain injury
Neuronal cell death contributes significantly to the pathology of traumatic brain injury (TBI) irrespective of the mode or severity of the injury. Activation of a pro-survival protein, Akt, is known to be regulated by an E3 ligase TRAF6 through a process of ubiquitination-coupled phosphorylation at...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763442/ https://www.ncbi.nlm.nih.gov/pubmed/23907468 http://dx.doi.org/10.1038/cddis.2013.280 |
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Enlace del recurso
por Farook, J M, Shields, J, Tawfik, A, Markand, S, Sen, T, Smith, S B, Brann, D, Dhandapani, K M, Sen, N
Publicado 2013
Enlace del recurso
Publicado 2013
Enlace del recurso
Online
Artículo
Texto