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Brimonidine promotes axon growth after optic nerve injury through Erk phosphorylation

It is well known that axons of the adult mammalian central nervous system have a very limited ability to regenerate after injury. Therefore, the neurodegenerative process of glaucoma results in irreversible functional deficits, such as blindness. Brimonidine (BMD) is an alpha2-adrenergic receptor ag...

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Detalles Bibliográficos
Autores principales: Fujita, Y, Sato, A, Yamashita, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763459/
https://www.ncbi.nlm.nih.gov/pubmed/23928702
http://dx.doi.org/10.1038/cddis.2013.298