Cargando…
Pro-apoptotic miRNA-128-2 modulates ABCA1, ABCG1 and RXRα expression and cholesterol homeostasis
Aberrant regulation of cholesterol homeostasis is associated with obesity as well as multiple types of cancer. However, the mechanism behind these is largely missing. Here, we show that microRNA (miRNA)-128-2 is not only a pro-apoptotic microRNA but it also alters the expression of genes involved in...
Autores principales: | Adlakha, Y K, Khanna, S, Singh, R, Singh, V P, Agrawal, A, Saini, N |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763462/ https://www.ncbi.nlm.nih.gov/pubmed/23990020 http://dx.doi.org/10.1038/cddis.2013.301 |
Ejemplares similares
-
miR-128 exerts pro-apoptotic effect in a p53 transcription-dependent and -independent manner via PUMA-Bak axis
por: Adlakha, Y K, et al.
Publicado: (2013) -
The Cholesterol Transporter ABCG1 Links Cholesterol Homeostasis and Tumor Immunity
por: Sag, Duygu, et al.
Publicado: (2015) -
Brain microRNAs and insights into biological functions and therapeutic potential of brain enriched miRNA-128
por: Adlakha, Yogita K, et al.
Publicado: (2014) -
Mangiferin promotes macrophage cholesterol efflux and protects against atherosclerosis by augmenting the expression of ABCA1 and ABCG1
por: Ren, Kun, et al.
Publicado: (2019) -
Rosmarinic Acid Increases Macrophage Cholesterol Efflux through Regulation of ABCA1 and ABCG1 in Different Mechanisms
por: Nyandwi, Jean-Baptiste, et al.
Publicado: (2021)